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Single amino acid mutation of SR-BI decreases infectivity of hepatitis C virus derived from cell culture in a cell culture model

AIM: To investigate the effect of a single amino acid mutation in human class B scavenger receptor I (SR-BI) on the infectivity of cell culture-derived hepatitis C virus (HCVcc) in SR-BI knock-down Huh7-siSR-BI cells. METHODS: Site-directed mutagenesis was used to construct the SR-BI S112F mutation,...

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Detalles Bibliográficos
Autores principales:	Gao, Rong, Gao, Wei, Xu, Gang, Xu, Jie, Ren, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Baishideng Publishing Group Inc 2017
Materias:	Basic Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537182/ https://www.ncbi.nlm.nih.gov/pubmed/28811710 http://dx.doi.org/10.3748/wjg.v23.i28.5158

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