Cargando…

UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization

Hypoxia-inducible factor 1 (HIF-1) has been recognized as an important mediator of the reprogramming of carbohydrate metabolic pathways from oxidative phosphorylation to accelerated glycolysis. Although this reprogramming has been associated with the antioxidant and radioresistant properties of canc...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakashima, Ryota, Goto, Yoko, Koyasu, Sho, Kobayashi, Minoru, Morinibu, Akiyo, Yoshimura, Michio, Hiraoka, Masahiro, Hammond, Ester M., Harada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537219/
https://www.ncbi.nlm.nih.gov/pubmed/28761052
http://dx.doi.org/10.1038/s41598-017-06605-1