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Soluble Epoxide Hydrolase Inhibition Protected against Angiotensin II-induced Adventitial Remodeling

Epoxyeicosatrienoic acids (EETs), the metabolites of cytochrome P450 epoxygenases derived from arachidonic acid, exert important biological activities in maintaining cardiovascular homeostasis. Soluble epoxide hydrolase (sEH) hydrolyzes EETs to less biologically active dihydroxyeicosatrienoic acids....

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Detalles Bibliográficos
Autores principales: Zhou, Chi, Huang, Jin, Li, Qing, Nie, Jiali, Xu, Xizhen, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537243/
https://www.ncbi.nlm.nih.gov/pubmed/28761179
http://dx.doi.org/10.1038/s41598-017-07512-1