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A dsRNA virus with filamentous viral particles

Viruses with double-stranded RNA genomes form isometric particles or are capsidless. Here we report a double-stranded RNA virus, Colletotrichum camelliae filamentous virus 1 (CcFV-1) isolated from a fungal pathogen, that forms filamentous particles. CcFV-1 has eight genomic double-stranded RNAs, ran...

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Autores principales: Jia, Hengxia, Dong, Kaili, Zhou, Lingling, Wang, Guoping, Hong, Ni, Jiang, Daohong, Xu, Wenxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537263/
https://www.ncbi.nlm.nih.gov/pubmed/28761042
http://dx.doi.org/10.1038/s41467-017-00237-9
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author Jia, Hengxia
Dong, Kaili
Zhou, Lingling
Wang, Guoping
Hong, Ni
Jiang, Daohong
Xu, Wenxing
author_facet Jia, Hengxia
Dong, Kaili
Zhou, Lingling
Wang, Guoping
Hong, Ni
Jiang, Daohong
Xu, Wenxing
author_sort Jia, Hengxia
collection PubMed
description Viruses with double-stranded RNA genomes form isometric particles or are capsidless. Here we report a double-stranded RNA virus, Colletotrichum camelliae filamentous virus 1 (CcFV-1) isolated from a fungal pathogen, that forms filamentous particles. CcFV-1 has eight genomic double-stranded RNAs, ranging from 990 to 2444 bp, encoding 10 putative open reading frames, of which open reading frame 1 encodes an RNA-dependent RNA polymerase and open reading frame 4 a capsid protein. When inoculated, the naked CcFV-1 double-stranded RNAs are infectious and induce the accumulation of the filamentous particles in vivo. CcFV-1 is phylogenetically related to Aspergillus fumigatus tetramycovirus-1 and Beauveria bassiana polymycovirus-1, but differs in morphology and in the number of genomic components. CcFV-1 might be an intermediate virus related to truly capsidated viruses, or might represent a distinct encapsidating strategy. In terms of genome and particle architecture, our findings are a significant addition to the knowledge of the virosphere diversity.
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spelling pubmed-55372632017-08-07 A dsRNA virus with filamentous viral particles Jia, Hengxia Dong, Kaili Zhou, Lingling Wang, Guoping Hong, Ni Jiang, Daohong Xu, Wenxing Nat Commun Article Viruses with double-stranded RNA genomes form isometric particles or are capsidless. Here we report a double-stranded RNA virus, Colletotrichum camelliae filamentous virus 1 (CcFV-1) isolated from a fungal pathogen, that forms filamentous particles. CcFV-1 has eight genomic double-stranded RNAs, ranging from 990 to 2444 bp, encoding 10 putative open reading frames, of which open reading frame 1 encodes an RNA-dependent RNA polymerase and open reading frame 4 a capsid protein. When inoculated, the naked CcFV-1 double-stranded RNAs are infectious and induce the accumulation of the filamentous particles in vivo. CcFV-1 is phylogenetically related to Aspergillus fumigatus tetramycovirus-1 and Beauveria bassiana polymycovirus-1, but differs in morphology and in the number of genomic components. CcFV-1 might be an intermediate virus related to truly capsidated viruses, or might represent a distinct encapsidating strategy. In terms of genome and particle architecture, our findings are a significant addition to the knowledge of the virosphere diversity. Nature Publishing Group UK 2017-08-01 /pmc/articles/PMC5537263/ /pubmed/28761042 http://dx.doi.org/10.1038/s41467-017-00237-9 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Jia, Hengxia
Dong, Kaili
Zhou, Lingling
Wang, Guoping
Hong, Ni
Jiang, Daohong
Xu, Wenxing
A dsRNA virus with filamentous viral particles
title A dsRNA virus with filamentous viral particles
title_full A dsRNA virus with filamentous viral particles
title_fullStr A dsRNA virus with filamentous viral particles
title_full_unstemmed A dsRNA virus with filamentous viral particles
title_short A dsRNA virus with filamentous viral particles
title_sort dsrna virus with filamentous viral particles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537263/
https://www.ncbi.nlm.nih.gov/pubmed/28761042
http://dx.doi.org/10.1038/s41467-017-00237-9
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