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A single-channel mechanism for pharmacological potentiation of GluN1/GluN2A NMDA receptors
NMDA receptors (NMDARs) contribute to several neuropathological processes. Novel positive allosteric modulators (PAMs) of NMDARs have recently been identified but their effects on NMDAR gating remain largely unknown. To this end, we tested the effect of a newly developed molecule UBP684 on GluN1/Glu...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537304/ https://www.ncbi.nlm.nih.gov/pubmed/28761055 http://dx.doi.org/10.1038/s41598-017-07292-8 |