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Introduction: MHC/KIR and governance of specificity

The MHC controls specificity, to ensure that appropriate immune responses are mounted to invading pathogens whilst maintaining tolerance to the host. It encodes molecules that act as sentinels, providing a snapshot of the health of the interior and exterior of the cell for immune surveillance. To ma...

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Detalles Bibliográficos
Autores principales: Kelly, Adrian, Trowsdale, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537316/
https://www.ncbi.nlm.nih.gov/pubmed/28695288
http://dx.doi.org/10.1007/s00251-017-0986-6