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Next-Generation Sequencing-based genomic profiling of brain metastases of primary ovarian cancer identifies high number of BRCA-mutations

Ovarian cancer represents the most common gynaecological malignancy and has the highest mortality of all female reproductive cancers. It has a rare predilection to develop brain metastases (BM). In this study, we evaluated the mutational profile of ovarian cancer metastases through Next-Generation S...

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Detalles Bibliográficos
Autores principales:	Balendran, S., Liebmann-Reindl, S., Berghoff, A. S., Reischer, T., Popitsch, N., Geier, C. B., Kenner, L., Birner, P., Streubel, B., Preusser, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2017
Materias:	Laboratory Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537326/ https://www.ncbi.nlm.nih.gov/pubmed/28497333 http://dx.doi.org/10.1007/s11060-017-2459-z

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