Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves

Sweet potato, Ipomoea batatas, is a widely cultivated vegetable worldwide. The leaves contain polyphenolic natural products called caffeoylquinic acids (CQAs), which possess biological activities including inhibition of aggregation of amyloid peptides. The present study describes an efficient extrac...

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Autores principales: Usuki, Toyonobu, Onda, Shingo, Yoshizawa-Fujita, Masahiro, Rikukawa, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537367/
https://www.ncbi.nlm.nih.gov/pubmed/28761111
http://dx.doi.org/10.1038/s41598-017-07291-9
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author Usuki, Toyonobu
Onda, Shingo
Yoshizawa-Fujita, Masahiro
Rikukawa, Masahiro
author_facet Usuki, Toyonobu
Onda, Shingo
Yoshizawa-Fujita, Masahiro
Rikukawa, Masahiro
author_sort Usuki, Toyonobu
collection PubMed
description Sweet potato, Ipomoea batatas, is a widely cultivated vegetable worldwide. The leaves contain polyphenolic natural products called caffeoylquinic acids (CQAs), which possess biological activities including inhibition of aggregation of amyloid peptides. The present study describes an efficient extraction and isolation procedure for CQAs from sweet potato leaves using a cellulose-dissolving ionic liquid. The results showed that, compared to methanol, use of 1-butyl-3-methylimidazolium chloride ([C(4)mim]Cl) allowed the extraction of a 6.5-fold greater amount of CQAs. This protocol will enable the efficient extraction of other organic compounds and biopolymers from natural materials.
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spelling pubmed-55373672017-08-03 Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves Usuki, Toyonobu Onda, Shingo Yoshizawa-Fujita, Masahiro Rikukawa, Masahiro Sci Rep Article Sweet potato, Ipomoea batatas, is a widely cultivated vegetable worldwide. The leaves contain polyphenolic natural products called caffeoylquinic acids (CQAs), which possess biological activities including inhibition of aggregation of amyloid peptides. The present study describes an efficient extraction and isolation procedure for CQAs from sweet potato leaves using a cellulose-dissolving ionic liquid. The results showed that, compared to methanol, use of 1-butyl-3-methylimidazolium chloride ([C(4)mim]Cl) allowed the extraction of a 6.5-fold greater amount of CQAs. This protocol will enable the efficient extraction of other organic compounds and biopolymers from natural materials. Nature Publishing Group UK 2017-07-31 /pmc/articles/PMC5537367/ /pubmed/28761111 http://dx.doi.org/10.1038/s41598-017-07291-9 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Usuki, Toyonobu
Onda, Shingo
Yoshizawa-Fujita, Masahiro
Rikukawa, Masahiro
Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_full Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_fullStr Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_full_unstemmed Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_short Use of [C(4)mim]Cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
title_sort use of [c(4)mim]cl for efficient extraction of caffeoylquinic acids from sweet potato leaves
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537367/
https://www.ncbi.nlm.nih.gov/pubmed/28761111
http://dx.doi.org/10.1038/s41598-017-07291-9
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