Activation of NLRP3 inflammasomes contributes to hyperhomocysteinemia-aggravated inflammation and atherosclerosis in apoE-deficient mice

Hyperhomocysteinemia (HHcy) has been shown to promote vascular inflammation and atherosclerosis, but the underlying mechanisms remain largely unknown. The NLRP3 inflammasome has been identified as the cellular machinery responsible for activation of inflammatory processes. In this study, we hypothes...

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Detalles Bibliográficos
Autores principales: Wang, Renqing, Wang, Yiqin, Mu, Nana, Lou, Xiaoying, Li, Weixuan, Chen, Yanming, Fan, Dong, Tan, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537437/
https://www.ncbi.nlm.nih.gov/pubmed/28394319
http://dx.doi.org/10.1038/labinvest.2017.30

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