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Electronic Structures of LNA Phosphorothioate Oligonucleotides

Important oligonucleotides in anti-sense research have been investigated in silico and experimentally. This involves quantum mechanical (QM) calculations and chromatography experiments on locked nucleic acid (LNA) phosphorothioate (PS) oligonucleotides. iso-potential electrostatic surfaces are essen...

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Detalles Bibliográficos
Autores principales:	Bohr, Henrik G., Shim, Irene, Stein, Cy, Ørum, Henrik, Hansen, Henrik F., Koch, Troels
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537454/ https://www.ncbi.nlm.nih.gov/pubmed/28918042 http://dx.doi.org/10.1016/j.omtn.2017.05.011

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