CD47 overexpression is associated with decreased neutrophil apoptosis/phagocytosis and poor prognosis in non-small-cell lung cancer patients

BACKGROUND: Non-small-cell lung cancer (NSCLC) patients often exhibit neutrophilia, which has been associated with poor clinical outcomes. However, the mechanisms that lead to neutrophilia have not been fully established. CD47 is an antiphagocytic molecule that promotes neutrophil recruitment. METHO...

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Detalles Bibliográficos
Autores principales: Barrera, Lourdes, Montes-Servín, Edgar, Hernandez-Martinez, Juan-Manuel, García-Vicente, María de los Ángeles, Montes-Servín, Elizabeth, Herrera-Martínez, Marytere, Crispín, José C, Borbolla-Escoboza, José Rafael, Arrieta, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537491/
https://www.ncbi.nlm.nih.gov/pubmed/28632731
http://dx.doi.org/10.1038/bjc.2017.173

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