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GATA3 interacts with and stabilizes HIF-1α to enhance cancer cell invasiveness
GATA binding protein 3 (GATA3) is indispensable in development of human organs. However, the role of GATA3 in cancers remains elusive. Hypoxia inducible factor (HIF)-1 plays an important role in pathogenesis of human cancers. Regulation of HIF-1α degradation is orchestrated through collaboration of...
Autores principales: | Lin, M-C, Lin, J-J, Hsu, C-L, Juan, H-F, Lou, P-J, Huang, M-C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537608/ https://www.ncbi.nlm.nih.gov/pubmed/28263977 http://dx.doi.org/10.1038/onc.2017.8 |
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