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Plasma REST: a novel candidate biomarker of Alzheimer’s disease is modified by psychological intervention in an at-risk population
The repressor element 1-silencing transcription (REST) factor is a key regulator of the aging brain’s stress response. It is reduced in conditions of stress and Alzheimer’s disease (AD), which suggests that increasing REST may be neuroprotective. REST can be measured peripherally in blood plasma. Ou...
Autores principales: | Ashton, N J, Hye, A, Leckey, C A, Jones, A R, Gardner, A, Elliott, C, Wetherell, J L, Lenze, E J, Killick, R, Marchant, N L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537638/ https://www.ncbi.nlm.nih.gov/pubmed/28585932 http://dx.doi.org/10.1038/tp.2017.113 |
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