Cargando…

LMP1 and Dynamic Progressive Telomere Dysfunction: A Major Culprit in EBV-Associated Hodgkin’s Lymphoma

Epstein–Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is expressed in germinal-center-derived, mononuclear Hodgkin (H) and multinuclear, diagnostic Reed–Sternberg (RS) cells in classical EBV-positive Hodgkin’s lymphoma (cHL). LMP1 expression in EBV-negative H-cell lines results in a sign...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knecht, Hans, Mai, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537656/ https://www.ncbi.nlm.nih.gov/pubmed/28654015 http://dx.doi.org/10.3390/v9070164

Ejemplares similares

Follicular dendritic cells display microvesicle-associated LMP1 in reactive germinal centers of EBV+ classic Hodgkin lymphoma
por: Uccini, Stefania, et al.
Publicado: (2019)

The Anti-Apoptotic Role of EBV-LMP1 in Lymphoma Cells
por: Zeng, Mei, et al.
Publicado: (2020)

EBV in Hodgkin Lymphoma
por: Massini, Giuseppina, et al.
Publicado: (2009)

PD-L1 and EBV LMP1 expressions in classic Hodgkin lymphomas and its correlation with clinicopathological parameters and prognosis
por: ÖZDEMİR, Süleyman, et al.
Publicado: (2022)

Genomic Instability: The Driving Force behind Refractory/Relapsing Hodgkin’s Lymphoma
por: Knecht, Hans, et al.
Publicado: (2013)

Frequent traces of EBV infection in Hodgkin and non-Hodgkin lymphomas classified as EBV-negative by routine methods: expanding the landscape of EBV-related lymphomas
por: Mundo, Lucia, et al.
Publicado: (2020)

Generating CTLs against the subdominant EBV LMP antigens by transit expression of an A20 inhibitor with EBV LMP proteins in human DCs
por: Hong, Bangxing, et al.
Publicado: (2011)

Aberrant Expression of ID2 protein and its correlation with EBV-LMP1 and P16(INK4A) in Classical Hodgkin Lymphoma in China
por: Zhao, Po, et al.
Publicado: (2008)

New Look of EBV LMP1 Signaling Landscape
por: Wang, Ling, et al.
Publicado: (2021)

Correction: Frequent traces of EBV infection in Hodgkin and non-Hodgkin lymphomas classified as EBV-negative by routine methods: expanding the landscape of EBV-related lymphomas
por: Mundo, Lucia, et al.
Publicado: (2020)

HSV-tk/GCV gene therapy mediated by EBV-LMP1 for EBV-associated cancer
por: Lifang, Yang, et al.
Publicado: (2008)

Identification of a novel variant of LMP-1 of EBV in patients with endemic Burkitt lymphoma in western Kenya
por: Wohlford, Eric M, et al.
Publicado: (2013)

Long-term Outcome of Extranodal NK/T Cell Lymphoma Patients Treated With Postremission Therapy Using EBV LMP1 and LMP2a-specific CTLs
por: Cho, Seok-Goo, et al.
Publicado: (2015)

EBV in situ hybridization study for non-Hodgkin's lymphomas.
por: Ko, Y. H., et al.
Publicado: (1994)

HLA Associations in Classical Hodgkin Lymphoma: EBV Status Matters
por: Huang, Xin, et al.
Publicado: (2012)

The Role of Epstein-Barr Virus LMP-1 Immunohistochemical Staining in Childhood Hodgkin Lymphoma
por: Tanyildiz, Hikmet Gulsah, et al.
Publicado: (2015)

Differential expression of EBV proteins LMP1 and BHFR1 in EBV-associated gastric and nasopharyngeal cancer tissues
por: WANG, AILIANG, et al.
Publicado: (2016)

Novel Bifunctional Affibody Molecules with Specific Binding to Both EBV LMP1 and LMP2 for Targeted Therapy of Nasopharyngeal Carcinoma
por: Kamara, Saidu, et al.
Publicado: (2023)

Serum EBV antibodies and LMP-1 in Polish patients with oropharyngeal and laryngeal cancer
por: Fołtyn, Sylwia, et al.
Publicado: (2017)

LMP1-EBV Gene Deletion Mutations and HLA Genotypes of Nasopharyngeal Cancer Patients in Vietnam
por: Trinh, Cua Thi Hong, et al.
Publicado: (2023)

Frequency of EBV LMP-1 Promoter and Coding Variations in Burkitt Lymphoma Samples in Africa and South America and Peripheral Blood in Uganda
por: Liao, Hsiao-Mei, et al.
Publicado: (2018)

The EBV-encoded Latent Membrane Proteins, LMP2A and LMP2B, Limit the Actions of Interferon by Targeting Interferon Receptors for Degradation
por: Shah, Khilan M., et al.
Publicado: (2009)

3D nuclear organization of telomeres in the Hodgkin cell lines U-HO1 and U-HO1-PTPN1: PTPN1 expression prevents the formation of very short telomeres including "t-stumps"
por: Knecht, Hans, et al.
Publicado: (2010)

Analysis of EBNA-1 and LMP-1 variants in diseases associated with EBV infection in Chinese children
por: Ai, Junhong, et al.
Publicado: (2012)

A Therapeutic Approach to Nasopharyngeal Carcinomas by DNAzymes Targeting EBV LMP-1 Gene
por: Yang, Lifang, et al.
Publicado: (2010)

EBV‐LMP1 induces APOBEC3s and mitochondrial DNA hypermutation in nasopharyngeal cancer
por: Wakae, Kousho, et al.
Publicado: (2020)

The Role of EBV-Encoded LMP1 in the NPC Tumor Microenvironment: From Function to Therapy
por: Lo, Angela Kwok-Fung, et al.
Publicado: (2021)

Loss of P16 Protein Expression and Its Association with Epstein-Barr Virus LMP-1 Expression in Hodgkin's Lymphoma
por: Irshaid, Fawzi, et al.
Publicado: (2013)

Latent membrane protein 1 (LMP1) expression in Hodgkin lymphoma and its correlation with clinical and histologic parameters
por: Hashmi, Atif Ali, et al.
Publicado: (2017)

Measurement of CD8(+) and CD4(+) T Cell Frequencies Specific for EBV LMP1 and LMP2a Using mRNA-Transfected DCs
por: Sohn, Dae-Hee, et al.
Publicado: (2015)

Seasonal differences in the onset of the EBV-positive and -negative forms of paediatric Hodgkin's lymphoma
por: Reiman, A, et al.
Publicado: (2003)

Expression of the Chemokine Receptor CCR1 in Burkitt Lymphoma Cell Lines Is Linked to the CD10-Negative Cell Phenotype and Co-Expression of the EBV Latent Genes EBNA2, LMP1, and LMP2
por: Zvejniece, Laura, et al.
Publicado: (2022)

Molecular Pathogenesis of Hodgkin Lymphoma: Past, Present, Future
por: Bienz, Marc, et al.
Publicado: (2020)

Composite Lymphoma with Follicular Lymphoma Transformation to Clonally Related Epstein–Barr Virus (EBV) Positive Diffuse Large B-Cell Lymphoma and EBV-PositiveClassic Hodgkin Lymphoma
por: Ryder, Christopher B., et al.
Publicado: (2023)

HHV8-positive, EBV-positive Hodgkin lymphoma-like large B cell lymphoma: expanding the spectrum of HHV8 and EBV-associated lymphoproliferative disorders
por: Sanchez, Sandra, et al.
Publicado: (2020)

Novel EBV LMP-2-affibody and affitoxin in molecular imaging and targeted therapy of nasopharyngeal carcinoma
por: Zhu, Shanli, et al.
Publicado: (2020)

The impact of HLA class I and EBV latency‐II antigen‐specific CD8(+) T cells on the pathogenesis of EBV(+) Hodgkin lymphoma
por: Jones, K., et al.
Publicado: (2015)

HLA expression and HLA type associations in relation to EBV status in Hispanic Hodgkin lymphoma patients
por: Fletcher, Luke B., et al.
Publicado: (2017)

Epstein-Barr virus BART microRNAs in EBV- associated Hodgkin lymphoma and gastric cancer
por: De Re, Valli, et al.
Publicado: (2020)

Febrile Hypotensive Reactions Following ABVD Chemotherapy in Patients With EBV-associated Classical Hodgkin Lymphoma
por: Bond, David A., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3fne1sg7a8of4i82k22nu4bji0