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Telomerase Induction in HPV Infection and Oncogenesis

Telomerase extends the repetitive DNA at the ends of linear chromosomes, and it is normally active in stem cells. When expressed in somatic diploid cells, it can lead to cellular immortalization. Human papillomaviruses (HPVs) are associated with and high-risk for cancer activate telomerase through t...

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Detalles Bibliográficos
Autor principal: Katzenellenbogen, Rachel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537672/
https://www.ncbi.nlm.nih.gov/pubmed/28698524
http://dx.doi.org/10.3390/v9070180