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Targeted O‐glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced‐stage bladder tumours
Bladder carcinogenesis and tumour progression is accompanied by profound alterations in protein glycosylation on the cell surface, which may be explored for improving disease management. In a search for prognosis biomarkers and novel therapeutic targets we have screened, using immunohistochemistry,...
Autores principales: | Cotton, Sofia, Azevedo, Rita, Gaiteiro, Cristiana, Ferreira, Dylan, Lima, Luís, Peixoto, Andreia, Fernandes, Elisabete, Neves, Manuel, Neves, Diogo, Amaro, Teresina, Cruz, Ricardo, Tavares, Ana, Rangel, Maria, Silva, André M. N., Santos, Lúcio Lara, Ferreira, José Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537688/ https://www.ncbi.nlm.nih.gov/pubmed/28156048 http://dx.doi.org/10.1002/1878-0261.12035 |
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