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Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial

This study aimed to evaluate the postprandial effects of high and low glycemic index (GI) breakfasts on vascular function. It was a crossover trial that included 40 young healthy adults (50% women), aged 20–40 years, who were recruited at primary care settings. They consumed three experimental break...

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Autores principales: Sanchez-Aguadero, Natalia, Patino-Alonso, Maria C., Mora-Simon, Sara, Gomez-Marcos, Manuel A., Alonso-Dominguez, Rosario, Sanchez-Salgado, Benigna, Recio-Rodriguez, Jose I., Garcia-Ortiz, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537827/
https://www.ncbi.nlm.nih.gov/pubmed/28686199
http://dx.doi.org/10.3390/nu9070712
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author Sanchez-Aguadero, Natalia
Patino-Alonso, Maria C.
Mora-Simon, Sara
Gomez-Marcos, Manuel A.
Alonso-Dominguez, Rosario
Sanchez-Salgado, Benigna
Recio-Rodriguez, Jose I.
Garcia-Ortiz, Luis
author_facet Sanchez-Aguadero, Natalia
Patino-Alonso, Maria C.
Mora-Simon, Sara
Gomez-Marcos, Manuel A.
Alonso-Dominguez, Rosario
Sanchez-Salgado, Benigna
Recio-Rodriguez, Jose I.
Garcia-Ortiz, Luis
author_sort Sanchez-Aguadero, Natalia
collection PubMed
description This study aimed to evaluate the postprandial effects of high and low glycemic index (GI) breakfasts on vascular function. It was a crossover trial that included 40 young healthy adults (50% women), aged 20–40 years, who were recruited at primary care settings. They consumed three experimental breakfasts in randomized order, each one separated by a 1-week washout period: (1) control conditions (only water); (2) low GI (LGI) breakfast (29.4 GI and 1489 KJ energy); and (3) high GI (HGI) breakfast (64.0 GI and 1318 KJ energy). Blood samples were collected at 60 and 120 min after each breakfast to determine glucose and insulin levels. Vascular parameters were measured at 15 min intervals. Augmentation index (AIx) was studied as a primary outcome. Secondary outcomes comprised glucose, insulin, heart rate (HR) and pulse pressures (PPs). We found a trend toward increased AIx, HR and PPs for the HGI versus the LGI breakfast. A significant interaction between the type of breakfast consumed and all measured parameters was identified (p < 0.05) except for central PP. Stratifying data by sex, this interaction remained significant for AIx and augmentation pressure only in males (p < 0.05). In conclusion, breakfast GI could affect postprandial vascular responses in young healthy adults.
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spelling pubmed-55378272017-08-04 Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial Sanchez-Aguadero, Natalia Patino-Alonso, Maria C. Mora-Simon, Sara Gomez-Marcos, Manuel A. Alonso-Dominguez, Rosario Sanchez-Salgado, Benigna Recio-Rodriguez, Jose I. Garcia-Ortiz, Luis Nutrients Article This study aimed to evaluate the postprandial effects of high and low glycemic index (GI) breakfasts on vascular function. It was a crossover trial that included 40 young healthy adults (50% women), aged 20–40 years, who were recruited at primary care settings. They consumed three experimental breakfasts in randomized order, each one separated by a 1-week washout period: (1) control conditions (only water); (2) low GI (LGI) breakfast (29.4 GI and 1489 KJ energy); and (3) high GI (HGI) breakfast (64.0 GI and 1318 KJ energy). Blood samples were collected at 60 and 120 min after each breakfast to determine glucose and insulin levels. Vascular parameters were measured at 15 min intervals. Augmentation index (AIx) was studied as a primary outcome. Secondary outcomes comprised glucose, insulin, heart rate (HR) and pulse pressures (PPs). We found a trend toward increased AIx, HR and PPs for the HGI versus the LGI breakfast. A significant interaction between the type of breakfast consumed and all measured parameters was identified (p < 0.05) except for central PP. Stratifying data by sex, this interaction remained significant for AIx and augmentation pressure only in males (p < 0.05). In conclusion, breakfast GI could affect postprandial vascular responses in young healthy adults. MDPI 2017-07-07 /pmc/articles/PMC5537827/ /pubmed/28686199 http://dx.doi.org/10.3390/nu9070712 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sanchez-Aguadero, Natalia
Patino-Alonso, Maria C.
Mora-Simon, Sara
Gomez-Marcos, Manuel A.
Alonso-Dominguez, Rosario
Sanchez-Salgado, Benigna
Recio-Rodriguez, Jose I.
Garcia-Ortiz, Luis
Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial
title Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial
title_full Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial
title_fullStr Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial
title_full_unstemmed Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial
title_short Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial
title_sort postprandial effects of breakfast glycemic index on vascular function among young healthy adults: a crossover clinical trial
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537827/
https://www.ncbi.nlm.nih.gov/pubmed/28686199
http://dx.doi.org/10.3390/nu9070712
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