Cargando…
Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial
This study aimed to evaluate the postprandial effects of high and low glycemic index (GI) breakfasts on vascular function. It was a crossover trial that included 40 young healthy adults (50% women), aged 20–40 years, who were recruited at primary care settings. They consumed three experimental break...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537827/ https://www.ncbi.nlm.nih.gov/pubmed/28686199 http://dx.doi.org/10.3390/nu9070712 |
_version_ | 1783254254659567616 |
---|---|
author | Sanchez-Aguadero, Natalia Patino-Alonso, Maria C. Mora-Simon, Sara Gomez-Marcos, Manuel A. Alonso-Dominguez, Rosario Sanchez-Salgado, Benigna Recio-Rodriguez, Jose I. Garcia-Ortiz, Luis |
author_facet | Sanchez-Aguadero, Natalia Patino-Alonso, Maria C. Mora-Simon, Sara Gomez-Marcos, Manuel A. Alonso-Dominguez, Rosario Sanchez-Salgado, Benigna Recio-Rodriguez, Jose I. Garcia-Ortiz, Luis |
author_sort | Sanchez-Aguadero, Natalia |
collection | PubMed |
description | This study aimed to evaluate the postprandial effects of high and low glycemic index (GI) breakfasts on vascular function. It was a crossover trial that included 40 young healthy adults (50% women), aged 20–40 years, who were recruited at primary care settings. They consumed three experimental breakfasts in randomized order, each one separated by a 1-week washout period: (1) control conditions (only water); (2) low GI (LGI) breakfast (29.4 GI and 1489 KJ energy); and (3) high GI (HGI) breakfast (64.0 GI and 1318 KJ energy). Blood samples were collected at 60 and 120 min after each breakfast to determine glucose and insulin levels. Vascular parameters were measured at 15 min intervals. Augmentation index (AIx) was studied as a primary outcome. Secondary outcomes comprised glucose, insulin, heart rate (HR) and pulse pressures (PPs). We found a trend toward increased AIx, HR and PPs for the HGI versus the LGI breakfast. A significant interaction between the type of breakfast consumed and all measured parameters was identified (p < 0.05) except for central PP. Stratifying data by sex, this interaction remained significant for AIx and augmentation pressure only in males (p < 0.05). In conclusion, breakfast GI could affect postprandial vascular responses in young healthy adults. |
format | Online Article Text |
id | pubmed-5537827 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-55378272017-08-04 Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial Sanchez-Aguadero, Natalia Patino-Alonso, Maria C. Mora-Simon, Sara Gomez-Marcos, Manuel A. Alonso-Dominguez, Rosario Sanchez-Salgado, Benigna Recio-Rodriguez, Jose I. Garcia-Ortiz, Luis Nutrients Article This study aimed to evaluate the postprandial effects of high and low glycemic index (GI) breakfasts on vascular function. It was a crossover trial that included 40 young healthy adults (50% women), aged 20–40 years, who were recruited at primary care settings. They consumed three experimental breakfasts in randomized order, each one separated by a 1-week washout period: (1) control conditions (only water); (2) low GI (LGI) breakfast (29.4 GI and 1489 KJ energy); and (3) high GI (HGI) breakfast (64.0 GI and 1318 KJ energy). Blood samples were collected at 60 and 120 min after each breakfast to determine glucose and insulin levels. Vascular parameters were measured at 15 min intervals. Augmentation index (AIx) was studied as a primary outcome. Secondary outcomes comprised glucose, insulin, heart rate (HR) and pulse pressures (PPs). We found a trend toward increased AIx, HR and PPs for the HGI versus the LGI breakfast. A significant interaction between the type of breakfast consumed and all measured parameters was identified (p < 0.05) except for central PP. Stratifying data by sex, this interaction remained significant for AIx and augmentation pressure only in males (p < 0.05). In conclusion, breakfast GI could affect postprandial vascular responses in young healthy adults. MDPI 2017-07-07 /pmc/articles/PMC5537827/ /pubmed/28686199 http://dx.doi.org/10.3390/nu9070712 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Sanchez-Aguadero, Natalia Patino-Alonso, Maria C. Mora-Simon, Sara Gomez-Marcos, Manuel A. Alonso-Dominguez, Rosario Sanchez-Salgado, Benigna Recio-Rodriguez, Jose I. Garcia-Ortiz, Luis Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial |
title | Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial |
title_full | Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial |
title_fullStr | Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial |
title_full_unstemmed | Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial |
title_short | Postprandial Effects of Breakfast Glycemic Index on Vascular Function among Young Healthy Adults: A Crossover Clinical Trial |
title_sort | postprandial effects of breakfast glycemic index on vascular function among young healthy adults: a crossover clinical trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537827/ https://www.ncbi.nlm.nih.gov/pubmed/28686199 http://dx.doi.org/10.3390/nu9070712 |
work_keys_str_mv | AT sanchezaguaderonatalia postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial AT patinoalonsomariac postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial AT morasimonsara postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial AT gomezmarcosmanuela postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial AT alonsodominguezrosario postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial AT sanchezsalgadobenigna postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial AT reciorodriguezjosei postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial AT garciaortizluis postprandialeffectsofbreakfastglycemicindexonvascularfunctionamongyounghealthyadultsacrossoverclinicaltrial |