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Stable engraftment of human microbiota into mice with a single oral gavage following antibiotic conditioning

BACKGROUND: Human microbiota-associated (HMA) animal models relying on germ-free recipient mice are being used to study the relationship between intestinal microbiota and human disease. However, transfer of microbiota into germ-free animals also triggers global developmental changes in the recipient...

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Detalles Bibliográficos
Autores principales: Staley, Christopher, Kaiser, Thomas, Beura, Lalit K., Hamilton, Matthew J., Weingarden, Alexa R., Bobr, Aleh, Kang, Johnthomas, Masopust, David, Sadowsky, Michael J., Khoruts, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537947/
https://www.ncbi.nlm.nih.gov/pubmed/28760163
http://dx.doi.org/10.1186/s40168-017-0306-2