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Generation and characterization of new monoclonal antibodies targeting the PHF1 and AT8 epitopes on human tau

Tauopathies are a group of neurodegenerative disorders, including Alzheimer’s disease, defined by the presence of brain pathological inclusions comprised of abnormally aggregated and highly phosphorylated tau protein. The abundance of brain tau aggregates correlates with disease severity and select...

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Detalles Bibliográficos
Autores principales:	Strang, Kevin H., Goodwin, Marshall S., Riffe, Cara, Moore, Brenda D., Chakrabarty, Paramita, Levites, Yona, Golde, Todd E., Giasson, Benoit I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537986/ https://www.ncbi.nlm.nih.gov/pubmed/28760159 http://dx.doi.org/10.1186/s40478-017-0458-0

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