Cargando…

Recent advances in understanding Pseudomonas aeruginosa as a pathogen

The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and i...

Descripción completa

Detalles Bibliográficos
Autores principales: Klockgether, Jens, Tümmler, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538032/
https://www.ncbi.nlm.nih.gov/pubmed/28794863
http://dx.doi.org/10.12688/f1000research.10506.1
_version_ 1783254289042374656
author Klockgether, Jens
Tümmler, Burkhard
author_facet Klockgether, Jens
Tümmler, Burkhard
author_sort Klockgether, Jens
collection PubMed
description The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and its interaction with the mammalian host as well as the role of the type III and type VI secretion systems in P. aeruginosa infection.
format Online
Article
Text
id pubmed-5538032
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher F1000Research
record_format MEDLINE/PubMed
spelling pubmed-55380322017-08-08 Recent advances in understanding Pseudomonas aeruginosa as a pathogen Klockgether, Jens Tümmler, Burkhard F1000Res Review The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and its interaction with the mammalian host as well as the role of the type III and type VI secretion systems in P. aeruginosa infection. F1000Research 2017-07-28 /pmc/articles/PMC5538032/ /pubmed/28794863 http://dx.doi.org/10.12688/f1000research.10506.1 Text en Copyright: © 2017 Klockgether J and Tümmler B http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Klockgether, Jens
Tümmler, Burkhard
Recent advances in understanding Pseudomonas aeruginosa as a pathogen
title Recent advances in understanding Pseudomonas aeruginosa as a pathogen
title_full Recent advances in understanding Pseudomonas aeruginosa as a pathogen
title_fullStr Recent advances in understanding Pseudomonas aeruginosa as a pathogen
title_full_unstemmed Recent advances in understanding Pseudomonas aeruginosa as a pathogen
title_short Recent advances in understanding Pseudomonas aeruginosa as a pathogen
title_sort recent advances in understanding pseudomonas aeruginosa as a pathogen
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538032/
https://www.ncbi.nlm.nih.gov/pubmed/28794863
http://dx.doi.org/10.12688/f1000research.10506.1
work_keys_str_mv AT klockgetherjens recentadvancesinunderstandingpseudomonasaeruginosaasapathogen
AT tummlerburkhard recentadvancesinunderstandingpseudomonasaeruginosaasapathogen