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Recent advances in understanding Pseudomonas aeruginosa as a pathogen
The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and i...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538032/ https://www.ncbi.nlm.nih.gov/pubmed/28794863 http://dx.doi.org/10.12688/f1000research.10506.1 |
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author | Klockgether, Jens Tümmler, Burkhard |
author_facet | Klockgether, Jens Tümmler, Burkhard |
author_sort | Klockgether, Jens |
collection | PubMed |
description | The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and its interaction with the mammalian host as well as the role of the type III and type VI secretion systems in P. aeruginosa infection. |
format | Online Article Text |
id | pubmed-5538032 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-55380322017-08-08 Recent advances in understanding Pseudomonas aeruginosa as a pathogen Klockgether, Jens Tümmler, Burkhard F1000Res Review The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and its interaction with the mammalian host as well as the role of the type III and type VI secretion systems in P. aeruginosa infection. F1000Research 2017-07-28 /pmc/articles/PMC5538032/ /pubmed/28794863 http://dx.doi.org/10.12688/f1000research.10506.1 Text en Copyright: © 2017 Klockgether J and Tümmler B http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Klockgether, Jens Tümmler, Burkhard Recent advances in understanding Pseudomonas aeruginosa as a pathogen |
title | Recent advances in understanding
Pseudomonas aeruginosa as a pathogen |
title_full | Recent advances in understanding
Pseudomonas aeruginosa as a pathogen |
title_fullStr | Recent advances in understanding
Pseudomonas aeruginosa as a pathogen |
title_full_unstemmed | Recent advances in understanding
Pseudomonas aeruginosa as a pathogen |
title_short | Recent advances in understanding
Pseudomonas aeruginosa as a pathogen |
title_sort | recent advances in understanding
pseudomonas aeruginosa as a pathogen |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538032/ https://www.ncbi.nlm.nih.gov/pubmed/28794863 http://dx.doi.org/10.12688/f1000research.10506.1 |
work_keys_str_mv | AT klockgetherjens recentadvancesinunderstandingpseudomonasaeruginosaasapathogen AT tummlerburkhard recentadvancesinunderstandingpseudomonasaeruginosaasapathogen |