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Extending TCGA queries to automatically identify analogous genomic data from dbGaP
Data sharing is critical to advance genomic research by reducing the demand to collect new data by reusing and combining existing data and by promoting reproducible research. The Cancer Genome Atlas (TCGA) is a popular resource for individual-level genotype-phenotype cancer related data. The Databas...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538035/ https://www.ncbi.nlm.nih.gov/pubmed/28794857 http://dx.doi.org/10.12688/f1000research.9837.1 |
_version_ | 1783254289750163456 |
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author | Wagner, Erin K. Raje, Satyajeet Amos, Liz Kurata, Jessica Badve, Abhijit S. Li, Yingquan Busby, Ben |
author_facet | Wagner, Erin K. Raje, Satyajeet Amos, Liz Kurata, Jessica Badve, Abhijit S. Li, Yingquan Busby, Ben |
author_sort | Wagner, Erin K. |
collection | PubMed |
description | Data sharing is critical to advance genomic research by reducing the demand to collect new data by reusing and combining existing data and by promoting reproducible research. The Cancer Genome Atlas (TCGA) is a popular resource for individual-level genotype-phenotype cancer related data. The Database of Genotypes and Phenotypes (dbGaP) contains many datasets similar to those in TCGA. We have created a software pipeline that will allow researchers to discover relevant genomic data from dbGaP, based on matching TCGA metadata. The resulting research provides an easy to use tool to connect these two data sources. |
format | Online Article Text |
id | pubmed-5538035 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | F1000Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-55380352017-08-08 Extending TCGA queries to automatically identify analogous genomic data from dbGaP Wagner, Erin K. Raje, Satyajeet Amos, Liz Kurata, Jessica Badve, Abhijit S. Li, Yingquan Busby, Ben F1000Res Software Tool Article Data sharing is critical to advance genomic research by reducing the demand to collect new data by reusing and combining existing data and by promoting reproducible research. The Cancer Genome Atlas (TCGA) is a popular resource for individual-level genotype-phenotype cancer related data. The Database of Genotypes and Phenotypes (dbGaP) contains many datasets similar to those in TCGA. We have created a software pipeline that will allow researchers to discover relevant genomic data from dbGaP, based on matching TCGA metadata. The resulting research provides an easy to use tool to connect these two data sources. F1000Research 2017-03-24 /pmc/articles/PMC5538035/ /pubmed/28794857 http://dx.doi.org/10.12688/f1000research.9837.1 Text en Copyright: © 2017 Wagner EK et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The author(s) is/are employees of the US Government and therefore domestic copyright protection in USA does not apply to this work. The work may be protected under the copyright laws of other jurisdictions when used in those jurisdictions. |
spellingShingle | Software Tool Article Wagner, Erin K. Raje, Satyajeet Amos, Liz Kurata, Jessica Badve, Abhijit S. Li, Yingquan Busby, Ben Extending TCGA queries to automatically identify analogous genomic data from dbGaP |
title | Extending TCGA queries to automatically identify analogous genomic data from dbGaP |
title_full | Extending TCGA queries to automatically identify analogous genomic data from dbGaP |
title_fullStr | Extending TCGA queries to automatically identify analogous genomic data from dbGaP |
title_full_unstemmed | Extending TCGA queries to automatically identify analogous genomic data from dbGaP |
title_short | Extending TCGA queries to automatically identify analogous genomic data from dbGaP |
title_sort | extending tcga queries to automatically identify analogous genomic data from dbgap |
topic | Software Tool Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538035/ https://www.ncbi.nlm.nih.gov/pubmed/28794857 http://dx.doi.org/10.12688/f1000research.9837.1 |
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