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Unexpected papilledema in a young male with Type 1 diabetes

In young patients with T1D, neurological manifestations of cerebral hypertension should suggest the possibility of a cerebral venous sinus thrombosis (CVST). In these patients an inherited prothrombotic risk factor, including factor V Leiden G1691A gene mutation, should be considered during an event...

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Detalles Bibliográficos
Autores principales: Paniagua, Juan A., Bahamondes, Rodrigo, Cano‐Sánchez, Antonio, Velasco, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538076/
https://www.ncbi.nlm.nih.gov/pubmed/28781853
http://dx.doi.org/10.1002/ccr3.1067
Descripción
Sumario:In young patients with T1D, neurological manifestations of cerebral hypertension should suggest the possibility of a cerebral venous sinus thrombosis (CVST). In these patients an inherited prothrombotic risk factor, including factor V Leiden G1691A gene mutation, should be considered during an event of thrombosis. Improving the glycemic control is the first factor that should be controlled in a patient who carries a genetic prothrombotic risk factor. Anticoagulant treatment should be started as son as CVST has been diagnosed. Long‐term antithrombotic treatment with tinzaparin 175 IU/kg/day, a low‐molecular weight heparin (LMWH), could be reliable and well tolerated, although an indefinite special follow‐up, including neurological controls, is advisable even in asymptomatic patients.