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Unexpected papilledema in a young male with Type 1 diabetes
In young patients with T1D, neurological manifestations of cerebral hypertension should suggest the possibility of a cerebral venous sinus thrombosis (CVST). In these patients an inherited prothrombotic risk factor, including factor V Leiden G1691A gene mutation, should be considered during an event...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538076/ https://www.ncbi.nlm.nih.gov/pubmed/28781853 http://dx.doi.org/10.1002/ccr3.1067 |
Sumario: | In young patients with T1D, neurological manifestations of cerebral hypertension should suggest the possibility of a cerebral venous sinus thrombosis (CVST). In these patients an inherited prothrombotic risk factor, including factor V Leiden G1691A gene mutation, should be considered during an event of thrombosis. Improving the glycemic control is the first factor that should be controlled in a patient who carries a genetic prothrombotic risk factor. Anticoagulant treatment should be started as son as CVST has been diagnosed. Long‐term antithrombotic treatment with tinzaparin 175 IU/kg/day, a low‐molecular weight heparin (LMWH), could be reliable and well tolerated, although an indefinite special follow‐up, including neurological controls, is advisable even in asymptomatic patients. |
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