Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide

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Neuregulin-1 (NRG1) and ErbB receptors have been associated with psychopathology, and NRG1-ErbB3 signaling has been shown to increase hippocampal neurogenesis and induce antidepressant-like effects. In this study, we aimed to determine whether deficits in NRG1 or ErbBs might be present in the hippoc...

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Detalles Bibliográficos
Autores principales: Mahar, I, Labonte, B, Yogendran, S, Isingrini, E, Perret, L, Davoli, M A, Rachalski, A, Giros, B, Turecki, G, Mechawar, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538115/
https://www.ncbi.nlm.nih.gov/pubmed/28675388
http://dx.doi.org/10.1038/tp.2017.132
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