Altered neurite morphology and cholinergic function of induced pluripotent stem cell-derived neurons from a patient with Kleefstra syndrome and autism

The aim of the present study was to establish an in vitro Kleefstra syndrome (KS) disease model using the human induced pluripotent stem cell (hiPSC) technology. Previously, an autism spectrum disorder (ASD) patient with Kleefstra syndrome (KS-ASD) carrying a deleterious premature termination codon...

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Detalles Bibliográficos
Autores principales: Nagy, J, Kobolák, J, Berzsenyi, S, Ábrahám, Z, Avci, H X, Bock, I, Bekes, Z, Hodoscsek, B, Chandrasekaran, A, Téglási, A, Dezső, P, Koványi, B, Vörös, E T, Fodor, L, Szél, T, Németh, K, Balázs, A, Dinnyés, A, Lendvai, B, Lévay, G, Román, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538124/
https://www.ncbi.nlm.nih.gov/pubmed/28742076
http://dx.doi.org/10.1038/tp.2017.144

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