Why could a woman have three Trisomy 21 pregnancies? – a case report

Mosaicism, an important cause for recurrent T21, should be suspected in families with more than one affected child wishing to receive prenatal counseling. Fluorescence in‐situ hybridization analysis in a large number of cells and in different tissue samples is critical for detecting low‐level mosaic...

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Detalles Bibliográficos
Autores principales: Magalhães, Magda, Marques, Cecília, Ramos, Fabiana, Jardim, Ana, Franco, Sofia, Coelho, Filomena, Carreira, Isabel, Moura, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538204/
https://www.ncbi.nlm.nih.gov/pubmed/28781828
http://dx.doi.org/10.1002/ccr3.997
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author Magalhães, Magda
Marques, Cecília
Ramos, Fabiana
Jardim, Ana
Franco, Sofia
Coelho, Filomena
Carreira, Isabel
Moura, Paulo
author_facet Magalhães, Magda
Marques, Cecília
Ramos, Fabiana
Jardim, Ana
Franco, Sofia
Coelho, Filomena
Carreira, Isabel
Moura, Paulo
author_sort Magalhães, Magda
collection PubMed
description Mosaicism, an important cause for recurrent T21, should be suspected in families with more than one affected child wishing to receive prenatal counseling. Fluorescence in‐situ hybridization analysis in a large number of cells and in different tissue samples is critical for detecting low‐level mosaicism and is a key prognostic factor.
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spelling pubmed-55382042017-08-04 Why could a woman have three Trisomy 21 pregnancies? – a case report Magalhães, Magda Marques, Cecília Ramos, Fabiana Jardim, Ana Franco, Sofia Coelho, Filomena Carreira, Isabel Moura, Paulo Clin Case Rep Case Reports Mosaicism, an important cause for recurrent T21, should be suspected in families with more than one affected child wishing to receive prenatal counseling. Fluorescence in‐situ hybridization analysis in a large number of cells and in different tissue samples is critical for detecting low‐level mosaicism and is a key prognostic factor. John Wiley and Sons Inc. 2017-06-15 /pmc/articles/PMC5538204/ /pubmed/28781828 http://dx.doi.org/10.1002/ccr3.997 Text en © 2017 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Magalhães, Magda
Marques, Cecília
Ramos, Fabiana
Jardim, Ana
Franco, Sofia
Coelho, Filomena
Carreira, Isabel
Moura, Paulo
Why could a woman have three Trisomy 21 pregnancies? – a case report
title Why could a woman have three Trisomy 21 pregnancies? – a case report
title_full Why could a woman have three Trisomy 21 pregnancies? – a case report
title_fullStr Why could a woman have three Trisomy 21 pregnancies? – a case report
title_full_unstemmed Why could a woman have three Trisomy 21 pregnancies? – a case report
title_short Why could a woman have three Trisomy 21 pregnancies? – a case report
title_sort why could a woman have three trisomy 21 pregnancies? – a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538204/
https://www.ncbi.nlm.nih.gov/pubmed/28781828
http://dx.doi.org/10.1002/ccr3.997
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