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CYP2C19 genetic variation and individualized clopidogrel prescription in a cardiology clinic

Background: Clopidogrel (Plavix) is an antiplatelet medication that is routinely used in patients with cardiovascular disease. Cytochrome P2C19 enzymes play a major role in its metabolism, which determines its varied therapeutic level and its effectiveness. Objectives: To customize clopidogrel thera...

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Detalles Bibliográficos
Autores principales: Mirabbasi, Seyed abbas, Khalighi, Koroush, Wu, Yin, Walker, Stanley, Khalighi, Bahar, Fan, Wuqiang, Kodali, Archana, Cheng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538219/
https://www.ncbi.nlm.nih.gov/pubmed/28808507
http://dx.doi.org/10.1080/20009666.2017.1347475