Cell-based, bioluminescent assay for monitoring the interaction between PCSK9 and the LDL receptor

Monitoring the expression of cell-surface receptors, their interaction with extracellular ligands, and their fate upon ligand binding is important for understanding receptor function and developing new therapies. We describe a cell-based method that utilizes bioluminescent protein complementation te...

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Detalles Bibliográficos
Autores principales: Duellman, Sarah J., Machleidt, Thomas, Cali, James J., Vidugiriene, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538273/
https://www.ncbi.nlm.nih.gov/pubmed/28611099
http://dx.doi.org/10.1194/jlr.D074658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538273/
https://www.ncbi.nlm.nih.gov/pubmed/28611099
http://dx.doi.org/10.1194/jlr.D074658

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