REST suppression mediates neural conversion of adult human fibroblasts via microRNA‐dependent and ‐independent pathways

Direct conversion of human fibroblasts into mature and functional neurons, termed induced neurons (iNs), was achieved for the first time 6 years ago. This technology offers a promising shortcut for obtaining patient‐ and disease‐specific neurons for disease modeling, drug screening, and other biomed...

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Detalles Bibliográficos
Autores principales: Drouin‐Ouellet, Janelle, Lau, Shong, Brattås, Per Ludvik, Rylander Ottosson, Daniella, Pircs, Karolina, Grassi, Daniela A, Collins, Lucy M, Vuono, Romina, Andersson Sjöland, Annika, Westergren‐Thorsson, Gunilla, Graff, Caroline, Minthon, Lennart, Toresson, Håkan, Barker, Roger A, Jakobsson, Johan, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538296/
https://www.ncbi.nlm.nih.gov/pubmed/28646119
http://dx.doi.org/10.15252/emmm.201607471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538296/
https://www.ncbi.nlm.nih.gov/pubmed/28646119
http://dx.doi.org/10.15252/emmm.201607471

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