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ApoE influences regional white-matter axonal density loss in Alzheimer's disease

Mechanisms underlying phenotypic heterogeneity in young onset Alzheimer disease (YOAD) are poorly understood. We used diffusion tensor imaging and neurite orientation dispersion and density imaging (NODDI) with tract-based spatial statistics to investigate apolipoprotein (APOE) ε4 modulation of whit...

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Detalles Bibliográficos
Autores principales:	Slattery, Catherine F., Zhang, Jiaying, Paterson, Ross W., Foulkes, Alexander J.M., Carton, Amelia, Macpherson, Kirsty, Mancini, Laura, Thomas, David L., Modat, Marc, Toussaint, Nicolas, Cash, David M., Thornton, John S., Henley, Susie M.D., Crutch, Sebastian J., Alexander, Daniel C., Ourselin, Sebastien, Fox, Nick C., Zhang, Hui, Schott, Jonathan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538347/ https://www.ncbi.nlm.nih.gov/pubmed/28578156 http://dx.doi.org/10.1016/j.neurobiolaging.2017.04.021

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