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GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression
The eIF4E homologous protein (4EHP) is thought to repress translation by competing with eIF4E for binding to the 5′ cap structure of specific mRNAs to which it is recruited through interactions with various proteins, including the GRB10-interacting GYF (glycine–tyrosine–phenylalanine domain) protein...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538437/ https://www.ncbi.nlm.nih.gov/pubmed/28698298 http://dx.doi.org/10.1101/gad.299420.117 |