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Single-cell DNA sequencing reveals a late-dissemination model in metastatic colorectal cancer

Metastasis is a complex biological process that has been difficult to delineate in human colorectal cancer (CRC) patients. A major obstacle in understanding metastatic lineages is the extensive intra-tumor heterogeneity at the primary and metastatic tumor sites. To address this problem, we developed...

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Detalles Bibliográficos
Autores principales:	Leung, Marco L., Davis, Alexander, Gao, Ruli, Casasent, Anna, Wang, Yong, Sei, Emi, Vilar, Eduardo, Maru, Dipen, Kopetz, Scott, Navin, Nicholas E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538546/ https://www.ncbi.nlm.nih.gov/pubmed/28546418 http://dx.doi.org/10.1101/gr.209973.116

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