Seasonality, Epidemiology and Outcome of Congenital Diaphragmatic Hernia in South West of Iran

INTRODUCTION : The pathogenesis of congenital diaphragmatic hernia (CDH) is not clear. Risk factors including environmental factors have been implicated in the pathogenesis of few congenital anomalies. We aimed to assess the effect of season on the incidence of CDH and mortality rate in the southwes...

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Detalles Bibliográficos
Autores principales: Dehdashtian, Masoud, Bashirnejad, Shiva, Malekian, Arash, Aramesh, Mohammad Reza, Aletayeb, Mohammad Hasan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EL-MED-Pub 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538594/
https://www.ncbi.nlm.nih.gov/pubmed/28770125
http://dx.doi.org/10.21699/jns.v6i2.506
Descripción
Sumario:INTRODUCTION : The pathogenesis of congenital diaphragmatic hernia (CDH) is not clear. Risk factors including environmental factors have been implicated in the pathogenesis of few congenital anomalies. We aimed to assess the effect of season on the incidence of CDH and mortality rate in the southwest of Iran. MATERIAL AND METHODS : In this retrospective study, the records of 60 patients with CDH who were admitted at Neonatal Intensive Care Unit (NICU) of Imam Khomeini Hospital of Ahvaz, Iran were evaluated. RESULTS : Assuming that all the neonates born with CDH in the region reach this hospital, overall CDH prevalence rate was 1.09 per 10 000 total births. Conceptions in spring and summer in this region had statistically significantly higher incidence of CDH. Survival rate in the series was 41.6%. CONCLUSION : Seasonal variation has impact on the incidence of CDH. Mortality rate in neonates with CDH is still very high.

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