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Biological evaluation of both enantiomers of fluoro-thalidomide using human myeloma cell line H929 and others

Over the last few years, thalidomide has become one of the most important anti-tumour drugs for the treatment of relapsed-refractory multiple myeloma. However, besides its undesirable teratogenic side effect, its configurational instability critically limits any further therapeutic improvements of t...

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Detalles Bibliográficos
Autores principales: Tokunaga, Etsuko, Akiyama, Hidehiko, Soloshonok, Vadim A., Inoue, Yuki, Hara, Hideaki, Shibata, Norio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538663/
https://www.ncbi.nlm.nih.gov/pubmed/28763493
http://dx.doi.org/10.1371/journal.pone.0182152