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Metabolic engineering of CHO cells for the development of a robust protein production platform

Chinese hamster ovary (CHO) cells are the most preferred mammalian host used for the bio-pharmaceutical production. A major challenge in metabolic engineering is to balance the flux of the tuned heterogonous metabolic pathway and achieve efficient metabolic response in a mammalian cellular system. P...

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Detalles Bibliográficos
Autores principales:	Gupta, Sanjeev Kumar, Srivastava, Santosh K., Sharma, Ankit, Nalage, Vaibhav H. H., Salvi, Darshita, Kushwaha, Hiralal, Chitnis, Nikhil B., Shukla, Pratyoosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538670/ https://www.ncbi.nlm.nih.gov/pubmed/28763459 http://dx.doi.org/10.1371/journal.pone.0181455

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