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Electrophysiological findings of Turkish patients with restless legs syndrome
We aimed to investigate changes in electrophysiological findings in Turkish patients with restless legs syndrome (RLS), including F-wave latency (FWL), peripheral silent period (PSP), and Hoffmann reflex. The study took place in a university hospital in Turkey and involved 30 newly diagnosed RLS pat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538691/ https://www.ncbi.nlm.nih.gov/pubmed/28794635 http://dx.doi.org/10.2147/NDT.S132903 |
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author | Özsimsek, Ahmet Koyuncuoglu, Hasan Rifat |
author_facet | Özsimsek, Ahmet Koyuncuoglu, Hasan Rifat |
author_sort | Özsimsek, Ahmet |
collection | PubMed |
description | We aimed to investigate changes in electrophysiological findings in Turkish patients with restless legs syndrome (RLS), including F-wave latency (FWL), peripheral silent period (PSP), and Hoffmann reflex. The study took place in a university hospital in Turkey and involved 30 newly diagnosed RLS patients and 30 healthy controls who were matched for age and gender. Participant’s demographics (age, gender, weight, and height), laboratory findings, and electrophysiological test outcomes were gathered and analyzed. There was no significant difference in the FWL of the median and ulnar nerves, whereas the H-wave maximum amplitude and H/M ratio were significantly higher in the RLS patients than in the controls at rest. All of the PSP parameters were similar between patients and controls for the abductor pollicis brevis and gastrocnemius muscles. However, for the tibialis anterior muscle, all the PSP duration parameters were shorter in the RLS patients, whereas the PSP latency parameters were similar. The data suggest that there may be a reduction in spinal segmental inhibition at the L4–L5–S1 level, but the mechanisms of inhibition at the L4–L5 and S1 levels may be different; furthermore, there may be no pathology in the peripheral nerves. Further prospective studies with larger cohorts are now needed to evaluate the pathophysiology of RLS with different neurophysiological assessment tools. |
format | Online Article Text |
id | pubmed-5538691 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-55386912017-08-09 Electrophysiological findings of Turkish patients with restless legs syndrome Özsimsek, Ahmet Koyuncuoglu, Hasan Rifat Neuropsychiatr Dis Treat Original Research We aimed to investigate changes in electrophysiological findings in Turkish patients with restless legs syndrome (RLS), including F-wave latency (FWL), peripheral silent period (PSP), and Hoffmann reflex. The study took place in a university hospital in Turkey and involved 30 newly diagnosed RLS patients and 30 healthy controls who were matched for age and gender. Participant’s demographics (age, gender, weight, and height), laboratory findings, and electrophysiological test outcomes were gathered and analyzed. There was no significant difference in the FWL of the median and ulnar nerves, whereas the H-wave maximum amplitude and H/M ratio were significantly higher in the RLS patients than in the controls at rest. All of the PSP parameters were similar between patients and controls for the abductor pollicis brevis and gastrocnemius muscles. However, for the tibialis anterior muscle, all the PSP duration parameters were shorter in the RLS patients, whereas the PSP latency parameters were similar. The data suggest that there may be a reduction in spinal segmental inhibition at the L4–L5–S1 level, but the mechanisms of inhibition at the L4–L5 and S1 levels may be different; furthermore, there may be no pathology in the peripheral nerves. Further prospective studies with larger cohorts are now needed to evaluate the pathophysiology of RLS with different neurophysiological assessment tools. Dove Medical Press 2017-07-27 /pmc/articles/PMC5538691/ /pubmed/28794635 http://dx.doi.org/10.2147/NDT.S132903 Text en © 2017 Özsimsek and Koyuncuoglu. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Özsimsek, Ahmet Koyuncuoglu, Hasan Rifat Electrophysiological findings of Turkish patients with restless legs syndrome |
title | Electrophysiological findings of Turkish patients with restless legs syndrome |
title_full | Electrophysiological findings of Turkish patients with restless legs syndrome |
title_fullStr | Electrophysiological findings of Turkish patients with restless legs syndrome |
title_full_unstemmed | Electrophysiological findings of Turkish patients with restless legs syndrome |
title_short | Electrophysiological findings of Turkish patients with restless legs syndrome |
title_sort | electrophysiological findings of turkish patients with restless legs syndrome |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538691/ https://www.ncbi.nlm.nih.gov/pubmed/28794635 http://dx.doi.org/10.2147/NDT.S132903 |
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