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Single stranded adeno-associated virus achieves efficient gene transfer to anterior segment in the mouse eye
Adeno-associated viruses (AAVs) are used extensively as a gene delivery vehicle for retinal gene therapy, yet its ability to target the anterior segment of the eye, critical to unlocking therapeutic opportunities, is less characterized. Previously, self-complimentary (sc) AAV was shown to be necessa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538712/ https://www.ncbi.nlm.nih.gov/pubmed/28763501 http://dx.doi.org/10.1371/journal.pone.0182473 |