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Evidence for a shape-based recognition of odorants in vivo in the human nose from an analysis of the molecular mechanism of lily-of-the-valley odorants detection in the Lilial and Bourgeonal family using the C/Si/Ge/Sn switch strategy

We performed an analysis of possible mechanisms of ligand recognition in the human nose. The analysis is based on in vivo odor threshold determination and in vitro Ca(2+) imaging assays with a C/Si/Ge/Sn switch strategy applied to the compounds Lilial and Bourgeonal, to differentiate between differe...

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Detalles Bibliográficos
Autores principales: Wolf, Steffen, Gelis, Lian, Dörrich, Steffen, Hatt, Hanns, Kraft, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538716/
https://www.ncbi.nlm.nih.gov/pubmed/28763484
http://dx.doi.org/10.1371/journal.pone.0182147