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Open and Closed Structures Reveal Allostery and Pliability in the HIV-1 Envelope Spike
For many enveloped viruses, binding to a receptor(s) on a host cell acts as a first step in a series of events culminating in fusion with the host cell membrane and transfer of genetic material for replication [for review see(1,2)]. The envelope glycoprotein (Env) trimer on the surface of HIV is res...
Autores principales: | Ozorowski, Gabriel, Pallesen, Jesper, de Val, Natalia, Lyumkis, Dmitry, Cottrell, Christopher A., Torres, Jonathan L., Copps, Jeffrey, Stanfield, Robyn L., Cupo, Albert, Pugach, Pavel, Moore, John P., Wilson, Ian A., Ward, Andrew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538736/ https://www.ncbi.nlm.nih.gov/pubmed/28700571 http://dx.doi.org/10.1038/nature23010 |
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