RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin

Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39 enzymes localize to their target genomic loci remains unclear. Here, we demonstrate that chromatin-associated RNA contributes to the stable as...

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Detalles Bibliográficos
Autores principales: Johnson, Whitney L, Yewdell, William T, Bell, Jason C, McNulty, Shannon M, Duda, Zachary, O’Neill, Rachel J, Sullivan, Beth A, Straight, Aaron F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538822/
https://www.ncbi.nlm.nih.gov/pubmed/28760200
http://dx.doi.org/10.7554/eLife.25299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538822/
https://www.ncbi.nlm.nih.gov/pubmed/28760200
http://dx.doi.org/10.7554/eLife.25299

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