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Energy imbalance alters Ca(2+) handling and excitability of POMC neurons
Satiety-signaling, pro-opiomelanocortin (POMC)-expressing neurons in the arcuate nucleus of the hypothalamus play a pivotal role in the regulation of energy homeostasis. Recent studies reported altered mitochondrial dynamics and decreased mitochondria- endoplasmic reticulum contacts in POMC neurons...
Autores principales: | Paeger, Lars, Pippow, Andreas, Hess, Simon, Paehler, Moritz, Klein, Andreas C, Husch, Andreas, Pouzat, Christophe, Brüning, Jens C, Kloppenburg, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538824/ https://www.ncbi.nlm.nih.gov/pubmed/28762947 http://dx.doi.org/10.7554/eLife.25641 |
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