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Next generation sequencing of carcinoma of unknown primary reveals novel combinatorial strategies in a heterogeneous mutational landscape
BACKGROUND: Advanced carcinoma of unknown primary (CUP) has limited effective therapeutic options given the phenotypic and genotypic diversity. To identify future novel therapeutic strategies we conducted an exploratory analysis of next-generation sequencing (NGS) of relapsed, refractory CUP. METHOD...
Autores principales: | Subbiah, Ishwaria M., Tsimberidou, Apostolia, Subbiah, Vivek, Janku, Filip, Roy-Chowdhuri, Sinchita, Hong, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538848/ https://www.ncbi.nlm.nih.gov/pubmed/28781987 http://dx.doi.org/10.18632/oncoscience.352 |
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