Ultra-high resolution X-ray structures of two forms of human recombinant insulin at 100 K

The crystal structure of a commercially available form of human recombinant (HR) insulin, Insugen (I), used in the treatment of diabetes has been determined to 0.92 Å resolution using low temperature, 100 K, synchrotron X-ray data collected at 16,000 keV (λ = 0.77 Å). Refinement carried out with ani...

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Detalles Bibliográficos
Autores principales: Lisgarten, David R., Palmer, Rex A., Lobley, Carina M. C., Naylor, Claire E., Chowdhry, Babur Z., Al-Kurdi, Zakieh I., Badwan, Adnan A., Howlin, Brendan J., Gibbons, Nicholas C. J., Saldanha, José W., Lisgarten, John N., Basak, Ajit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539060/
https://www.ncbi.nlm.nih.gov/pubmed/29086855
http://dx.doi.org/10.1186/s13065-017-0296-y

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