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Nebivolol Desensitizes Myofilaments of a Hypertrophic Cardiomyopathy Mouse Model
Background: Hypertrophic cardiomyopathy (HCM) patients often present with diastolic dysfunction and a normal to supranormal systolic function. To counteract this hypercontractility, guideline therapies advocate treatment with beta-adrenoceptor and Ca(2+) channel blockers. One well established pathom...
Autores principales: | Stücker, Sabrina, Kresin, Nico, Carrier, Lucie, Friedrich, Felix W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539082/ https://www.ncbi.nlm.nih.gov/pubmed/28824454 http://dx.doi.org/10.3389/fphys.2017.00558 |
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