ARC is essential for maintaining pancreatic islet structure and β-cell viability during type 2 diabetes

Pancreatic β-cell loss through apoptosis is an important disease mechanism in type 2 diabetes. Apoptosis Repressor with CARD (ARC) is a cell death inhibitor that antagonizes multiple death programs. We previously reported that ARC is abundant in pancreatic β-cells and modulates survival of these cel...

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Detalles Bibliográficos
Autores principales: McKimpson, Wendy M., Zheng, Min, Chua, Streamson C., Pessin, Jeffrey E., Kitsis, Richard N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539143/
https://www.ncbi.nlm.nih.gov/pubmed/28765602
http://dx.doi.org/10.1038/s41598-017-07107-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539143/
https://www.ncbi.nlm.nih.gov/pubmed/28765602
http://dx.doi.org/10.1038/s41598-017-07107-w

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