Antitumoral effects of γCdcPLI, a PLA(2) inhibitor from Crotalus durissus collilineatus via PI3K/Akt pathway on MDA-MB-231 breast cancer cell

Phospholipases A(2) (PLA(2)s) overexpression is closely associated with the malignant potential of breast cancers. Here, we showed for the first the antitumoral effects of γCdcPLI, a PLA(2) inhibitor from Crotalus durissus collilineatus via PI3K/Akt pathway on MDA-MB-231 cell. Firstly, γCdcPLI was m...

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Detalles Bibliográficos
Autores principales: Gimenes, Sarah N. C., Lopes, Daiana S., Alves, Patrícia T., Azevedo, Fernanda V. P. V., Vecchi, Lara, Goulart, Luiz R., Rodrigues, Thais C. S., Santos, André L. Q., Brites, Vera L. de C., Teixeira, Thaise L., da Silva, Cláudio V., Dias, Matheus H., Teixeira, Samuel C., Rodrigues, Renata S., Yoneyama, Kelly A. G., Oliveira, Ricardo A., Rodrigues, Veridiana de M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539153/
https://www.ncbi.nlm.nih.gov/pubmed/28765552
http://dx.doi.org/10.1038/s41598-017-07082-2

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