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Mast Cell Coupling to the Kallikrein–Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease

During the course of Chagas disease, infectious forms of Trypanosoma cruzi are occasionally liberated from parasitized heart cells. Studies performed with tissue culture trypomastigotes (TCTs, Dm28c strain) demonstrated that these parasites evoke neutrophil/CXCR2-dependent microvascular leakage by a...

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Detalles Bibliográficos
Autores principales:	Nascimento, Clarissa R., Andrade, Daniele, Carvalho-Pinto, Carla Eponina, Serra, Rafaela Rangel, Vellasco, Lucas, Brasil, Guilherme, Ramos-Junior, Erivan Schnaider, da Mota, Julia Barbalho, Almeida, Larissa Nogueira, Andrade, Marcus V., Correia Soeiro, Maria de Nazaré, Juliano, Luiz, Alvarenga, Patrícia Hessab, Oliveira, Ana Carolina, Sicuro, Fernando Lencastre, de Carvalho, Antônio C. Campos, Svensjö, Erik, Scharfstein, Julio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539176/ https://www.ncbi.nlm.nih.gov/pubmed/28824610 http://dx.doi.org/10.3389/fimmu.2017.00840

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