HM015k, a Novel Silybin Derivative, Multi-Targets Metastatic Ovarian Cancer Cells and Is Safe in Zebrafish Toxicity Studies

This study was designed to determine the in vitro mechanisms by which the novel silybin derivative, (E)-3-(3-(benzyloxy) phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (HM015k or 15k), produces its anticancer efficacy in ovarian cancer cells. Compound 15k induced apoptosis in ovarian cancer cells in a t...

Descripción completa

Detalles Bibliográficos
Autores principales: Amawi, Haneen, Hussein, Noor A., Karthikeyan, Chandrabose, Manivannan, Elangovan, Wisner, Alexander, Williams, Frederick E., Samuel, Temesgen, Trivedi, Piyush, Ashby, Charles R., Tiwari, Amit K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539246/
https://www.ncbi.nlm.nih.gov/pubmed/28824426
http://dx.doi.org/10.3389/fphar.2017.00498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539246/
https://www.ncbi.nlm.nih.gov/pubmed/28824426
http://dx.doi.org/10.3389/fphar.2017.00498

Ejemplares similares