Expression of Programmed Cell Death Protein 1 by Tumor-Infiltrating Lymphocytes and Tumor Cells is Associated with Advanced Tumor Stage in Patients with Esophageal Adenocarcinoma

BACKGROUND: Despite recent advances in the therapy for adenocarcinoma of the esophagogastric junction (AEG), overall prognosis remains poor. Programmed cell death protein 1 (PD1) is a co-inhibitory receptor primarily expressed by T-cells. Tumor cells can escape anticancer immune responses by trigger...

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Detalles Bibliográficos
Autores principales: Kollmann, Dagmar, Ignatova, Desislava, Jedamzik, Julia, Chang, Yun-Tsan, Jomrich, Gerd, Paireder, Matthias, Kristo, Ivan, Kazakov, Dmitry, Michal, Michal, Cozzio, Antonio, Hoetzenecker, Wolfram, Schatton, Tobias, Asari, Reza, Preusser, Matthias, Guenova, Emmanuella, Schoppmann, Sebastian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Gastrointestinal Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539275/
https://www.ncbi.nlm.nih.gov/pubmed/28429196
http://dx.doi.org/10.1245/s10434-017-5858-7

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