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Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas

Ciliary neurotrophic factor receptor α subunit (CNTFRα) and CNTF play important roles in neuron survival, glial differentiation and brain tumor growth. However, the molecular mechanisms of CNTFRα regulation and its clinical significance in glioma remain largely unknown. Here, we found CNTFRα was ove...

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Detalles Bibliográficos
Autores principales:	Fan, Kun, Wang, Xiaowen, Zhang, Jingwen, Ramos, Romela Irene, Zhang, Haibo, Li, Chunjie, Ye, Dan, Kang, Jiansheng, Marzese, Diego M., Hoon, Dave S. B., Hua, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539284/ https://www.ncbi.nlm.nih.gov/pubmed/28765641 http://dx.doi.org/10.1038/s41598-017-07124-9

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