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Blood-testis barrier integrity depends on Pin1 expression in Sertoli cells

The conformation and function of a subset of serine and threonine-phosphorylated proteins are regulated by the prolyl isomerase Pin1 through isomerization of phosphorylated Ser/Thr-Pro bonds. Pin1 is intensely expressed in Sertoli cells, but its function in this post mitotic cell remains unclear. Ou...

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Detalles Bibliográficos
Autores principales: Islam, Rabia, Yoon, Heein, Kim, Bong-soo, Bae, Han-sol, Shin, Hye-rim, Kim, Woo-Jin, Yoon, Won-joon, Lee, Yun-Sil, Woo, Kyung Mi, Baek, Jeong-Hwa, Ryoo, Hyun-Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539286/
https://www.ncbi.nlm.nih.gov/pubmed/28765625
http://dx.doi.org/10.1038/s41598-017-07229-1